Publication Date:
2013-11-06
Description:
During late Schwann cell development, immature Schwann cells segregate large axons from bundles, a process called “axonal radial sorting.” Here we demonstrate that canonical Wnt signals play a critical role in radial sorting and assign a role to Wnt and Rspondin ligands in this process. Mice carrying β-catenin loss-of-function mutations...
Print ISSN:
0027-8424
Electronic ISSN:
1091-6490
Topics:
Biology
,
Medicine
,
Natural Sciences in General
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