ISSN:
0306-042X
Schlagwort(e):
Chemistry
;
Analytical Chemistry and Spectroscopy
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
The electron impact mass spectral behaviour of 14 synthetically prepared mercapturic acid methyl esters was examined. The most important and characteristic fragmentation reactions are discussed and special emphasis is made on the occurrence and the mechanism of two fragmentation pathways, which were recognized as ‘retro-Michael’ reactions. In principle, each reaction may result in the formation of two typical ions. In addition, three characteristic ‘key-ions’ originating from the N-acetyl(-l-)cysteine methyl ester part of the mercapturic acids were recognized in all mercapturic acid methyl esters investigated; these ‘key-ions’ can most probably be used as a tool for the qualitative as well as the quantitative analysis of mercapturic acids by gas chromatogra-phy mass spectrometry in biological fluids.
Zusätzliches Material:
4 Ill.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/bms.1200101107
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