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  • 1
    Monograph available for loan
    Monograph available for loan
    The lognormal distribution : with special reference to its uses in economics (1957)
    Cambridge : Univ. Press
    Details Availability
    Call number: MOP 42571
    Type of Medium: Monograph available for loan
    Pages: XVIII, 176 S.
    Series Statement: Monographs / University of Cambridge, Department of Applied Economics 5
    Location: MOP - must be ordered
    Branch Library: GFZ Library
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  • 2
    Electronic Resource
    Electronic Resource
    Peroxisome biogenesis in yeast (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Molecular microbiology 6 (1992), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Eukaryotic cells have evolved a complex set of intracellular organelles, each of which possesses a specific complement of enzymes and performs unique metabolic functions. This compartmentalization of cellular functions provides a level of metabolic control not available to prokaryotes. However, it presents the eukaryotic cell with the problem of targeting proteins to their specific location (s). Proteins must be efficiently transported from their site of synthesis in the cytosol to their specific organelle (s). Such a process may require translocation across one or more hydrophobic membrane barriers and/or asymmetric integration into specific membranes.Proteins carry cis-acting amino acid sequences that serve to act as recognition motifs for protein sorting and for the cellular translocation machinery. Sequences that target proteins to the endoplasmic reticulum/ secretory pathway, mitochondria, and chloroplasts are often present as cleavable amino-terminal extensions. In contrast, most peroxisomal proteins are synthesized at their mature size and are translocated to the organelle without any post-translational modification. This review will summarize what is known about how yeast solve the problem of specifically importing proteins into peroxisomes and will suggest future directions for investigations into peroxisome biogenesis in yeast.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2958.1992.tb01780.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    COMPARISON OF DIMETHYL SULFOXIDE LEVELS IN WHOLE BLOOD AND SERUM USING AN AUTOSAMPLER-EQUIPPED GAS CHROMATOGRAPH (1983)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 411 (1983), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1983.tb47317.x
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  • 4
    Electronic Resource
    Electronic Resource
    Dual feedback loops in the GAL regulon suppress cellular heterogeneity in yeast (2006)
    [s.l.] : Nature Publishing Group
    Nature genetics 38 (2006), S. 1082-1087 
    Details
    ISSN: 1546-1718
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Transcriptional noise is known to be an important cause of cellular heterogeneity and phenotypic variation. The extent to which molecular interaction networks may have evolved to either filter or exploit transcriptional noise is a much debated question. The yeast genetic network regulating ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/ng1869
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  • 5
    Electronic Resource
    Electronic Resource
    Cell biology Pore puzzle (2007)
    [s.l.] : Nature Publishing Group
    Nature 450 (2007), S. 621-622 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Consider a 1,000-piece jigsaw puzzle. There are millions of ways in which the pieces might fit together, yet there is only one solution. We solve the puzzle by considering each piece and ruling out those that don't fit physical restraints, such as colour patterns, the overall shape of the picture ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/450621a
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  • 6
    Electronic Resource
    Electronic Resource
    The statistical analysis of geochemical compositions (1984)
    Springer
    Mathematical geology 16 (1984), S. 531-564 
    Details
    ISSN: 1573-8868
    Keywords: Closure ; closed number system ; logistic ; logratio ; geochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Mathematics
    Notes: Abstract The analysis and interpretation of compositional data, such as major oxide compositions of rocks, has been traditionally plagued by the so-called constant-sum or closure problem. Particular difficulties have been the lack of a satisfactory, interpretable covariance structure and of rich, tractable, parametric classes of distributions on the simplex sample space. Consideration of logistic and logratio transformations between the simplex and Euclidan space has allowed the introduction of new concepts of covariance structure and of classes of logistic-normal distributions which have now opened up a substantial and meaningful array of statistical methodology for compositional data. From the motivation of a wide variety of practical geological problems we examine the range of possibilities with this new approach to the constant-sum problem.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01029316
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  • 7
    Electronic Resource
    Electronic Resource
    On criteria for measures of compositional difference (1992)
    Springer
    Mathematical geology 24 (1992), S. 365-379 
    Details
    ISSN: 1573-8868
    Keywords: scale invariance ; permutation invariance ; perturbation invariance ; covariance structure ; subcomposition ; equivalence classes ; groups
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Mathematics
    Notes: Abstract Simple perceptions about the nature of compositions lead through logical necessity to certain forms of analysis of compositional data. In this paper the consequences of essential requirements of scale, perturbation and permutation invariance, together with that of subcompositional dominance, are applied to the problem of characterizing change and measures of difference between two compositions. It will be shown that one strongly advocated scalar measure of difference fails these tests of logical necessity, and that one particular form of scalar measure of difference (the sum of the squares of all possible logratio differences in the components of the two compositions), although not unique, emerges as the simplest and most tractable satisfying the criteria.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00891269
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  • 8
    Electronic Resource
    Electronic Resource
    Logratios and Natural Laws in Compositional Data Analysis (1999)
    Springer
    Mathematical geology 31 (1999), S. 563-580 
    Details
    ISSN: 1573-8868
    Keywords: logcontrast principal component analysis ; raw correlation misinterpretation ; subcompositional hypotheses ; subcompositional coherence ; variability of olivines
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Mathematics
    Notes: Abstract The impossibility of interpreting correlations of raw compositional components and associated statistical methods has been clearly demonstrated over the last four decades and alternative statistical methodology developed. Despite this a return to the “traditional” use of raw components has been advocated recently and alternative methodology such as logratio analysis strongly criticized. This paper exposes the fallacies in this recent advocacy and demonstrates the constructive role that logratio analysis can play in geological compositional problems, in particular in the investigation of natural laws and in subcompositional investigations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1007568008032
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  • 9
    Electronic Resource
    Electronic Resource
    A plea for precision inMathematical Geology (1991)
    Springer
    Mathematical geology 23 (1991), S. 1081-1083 
    Details
    ISSN: 1573-8868
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Mathematics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02066112
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  • 10
    Electronic Resource
    Electronic Resource
    Reply to “interpreting and testing compositional data” by Alex Woronow, Karen M. Love, and John C. Butler (1989)
    Springer
    Mathematical geology 21 (1989), S. 65-71 
    Details
    ISSN: 1573-8868
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Mathematics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00897241
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