ALBERT

Beschreibung: A tissue-equivalent proportional counter spectrometer capable of measuring the absorbed dose and dose distribution as a function of LET and time, for all penetrating radiation in space, is described. This instrument weighs about 0.7 kg and was flown on the STS-31 (28.5 deg x 620 km) flight of the Space Shuttle, 24-29 April 1990. The measured total dose is in excellent agreement with the calculations based on the AP8MAX model of the trapped radiation belt protons. The observed LET frequency distribution is also in excellent agreement with calculations based on this model. Active instruments can provide more detailed dosimetry for crew risk assessment than the thermoluminescent detectors or a plastic track detector system.

Beschreibung: The closed environment and limited evasive capabilities inherent in space flight cause astronauts to be exposed to many potential harmful agents (chemical contaminants in the environment and cosmic radiation exposure). Current power systems used to achieve space flight are prohibitively expensive for supporting the weight requirements to fully shield astronauts from cosmic radiation. Therefore, radiation poses a major, currently unresolvable risk for astronauts, especially for long-duration space flights. The major detrimental radiation effects that are of primary concern for long-duration space flights are damage to the lens of the eye, damage to the immune system, damage to the central nervous system, and cancer. In addition to the direct damage to biological molecules in cells, radiation exposure induces oxidative damage. Many natural antioxidants, whether consumed before or after radiation exposure, are able to confer some level of radioprotection. In addition to achieving beneficial effects from long-known antioxidants such as vitamins E and C and folic acid, some protection is conferred by several recently discovered antioxidant molecules, such as flavonoids, epigallocatechin, and other polyphenols. Somewhat counterintuitive is the protection provided by diets containing elevated levels of omega-3 polyunsaturated fatty acids, considering they are thought to be prone to peroxidation. Even with the information we have at our disposal, it will be difficult to predict the types of dietary modifications that can best reduce the risk of radiation exposure to astronauts, those living on Earth, or those enduring diagnostic or therapeutic radiation exposure. Much more work must be done in humans, whether on Earth or, preferably, in space, before we are able to make concrete recommendations.