ALBERT — All Library Books, journals and Electronic Records Telegrafenberg

Hits per page

hit 1 - 1 | 1 hit

Sorting

Electronic Resource

Using purified P-glycoprotein to understand multidrug resistance (1995)

Shapiro, Adam B. ; Ling, Victor

Springer

Journal of bioenergetics and biomembranes 27 (1995), S. 7-13

add to mindlist on the mindlist

Details

ISSN: 1573-6881

Keywords: P-glycoprotein ; multidrug resistance

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Chemistry and Pharmacology , Physics

Notes: Abstract Since P-glycoprotein was discovered almost 20 years ago, its causative role in multidrug resistance has been established, but central problems of its biochemistry have not been definitively resolved. Recently, major advances have been made in P-glycoprotein biochemistry with the use of purified and reconstituted P-glycoprotein, as well as membranes from nonmammalian cells containing heterologously expressed P-glycoprotein. In this review we describe recent findings using these systems which are elucidating the molecular mechanism of P-glycoprotein-mediated drug transport.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF02110325

Permalink

	Location	Call Number	Expected	Availability

Others were also interested in ...

Paper (German National Licenses)

Fulltext

hit 1 - 1 | 1 hit