ISSN:
1573-0689
Keywords:
Microdialaysis
;
adsorption isotherms
;
biological membranes
;
tetraphenylboron
;
9-aminoacridine
;
mathematical model
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Physics
Notes:
Abstract We analyze the diffusion of hydrophobic molecules in a dialysis apparatus with respect to their adsorption on biological membrane vesicles confined to one dialysis chamber. The process is described with a kinetic model, which shows that, depending on the pattern of the adsorption isotherm, the kinetic parameter of the diffusion process through the dialysis membrane is up to two-fold increased by the presence of the adsorbing vesicle surface. The model successfully describes the diffusion of tetraphenylborate and 9-aminoacridine in the presence of chromatophores from photosynthetic membrane, with which they interact with hyperbolic and S-shaped isotherms, respectively.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00700470
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