ISSN:
1420-9071
Keywords:
Phytoalexins
;
growth inhibitory
;
transformed cells
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary We have tested the effect of the phytoalexins lubimin, (−)-maackiain and pinosylvin and the related compounds dehydroloroglossol and hordatine M on the growth of the human lymphoblastoid cell lines Molt and Raji. (−)-maackiain, pinosylvin and dehydroloroglossol showed significant growth inhibitory action on the cells. Suppression of [3H] thymidine and [3H] leucine uptake was tested and noted in pinosylvin and dehydroloroglossol. The phytoalexins and related compounds are widespread in plants and provide a potential source of antineoplastic substances.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01946707
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