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  • Organic Chemistry  (1)
  • insulin-producing tumour cells  (1)
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  • 1
    Electronic Resource
    Electronic Resource
    Metallporphyrinkomplexe. VIV. Mitt.: Pharmazie 36, 383 (1981)., Synthese von Polymethacrylsäureestern mit kovalent gebundenem Eisen(III)-protoporphyrin IX (1982)
    New York, NY : Wiley-Blackwell
    Journal für Praktische Chemie/Chemiker-Zeitung 324 (1982), S. 117-124 
    Details
    ISSN: 0021-8383
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Metalloporphyrin Complexes. VI. Synthesis of Polymethacrylates with Covalently Bound Iron (III)-protoporphyrin IXConvenient synthesis of polymeric iron (III)-protoporphyrin IX (hemin) compounds is described. The covalent linkage via the carboxylic groups of hemin is possible by the reaction of the activated ester of hemin with polymethacrylates containing aliphatic amino groups. Polymethacrylates with aromatic amino groups are suitable to immobilize the hemin via its methine bridges. The hemin-containing polymers are characterized by visible spectra and e.p.r.-spectroscopy.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/prac.19823240115
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  • 2
    Electronic Resource
    Electronic Resource
    Adenylate cyclase in membrane fractions of RIN-A2-cells: Studies with forskolin, NaF, GppNHp and NEM (1988)
    New York, NY [u.a.] : Wiley-Blackwell
    Cell Biochemistry and Function 6 (1988), S. 131-135 
    Details
    ISSN: 0263-6484
    Keywords: Adenylate cyclase ; insulin-producing tumour cells ; N-proteins ; forskolin ; GppNHp ; thiols ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: In crude membrane fractions of rat pancreatic islets and of RIN-A2-cells, forskolin and NaF stimulated adenylate cyclase activity. Basal and stimulated enzyme activity was approximately 3 to 6 fold higher in membranes of RIN-A2-cells than in membranes of islet cells. In RIN-A2-cells GppNHp and NEM inhibited forskolin-stimulated cyclase system of RIN-A2-cells contains inhibitory and stimulatory N-proteins and that there are critical thiols related to Ni, Ns and/or the catalytic unit. Thus, membrane fractions of RIN-A2-cells may be an appropriate model for studies on the adenylate cyclase system of insulin-producing cells.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cbf.290060208
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    Paper (German National Licenses)
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