ISSN:
1432-1017
Keywords:
Model endplate current
;
Transmitter secretion
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Physics
Notes:
Abstract Quantification of the time course and amplitude of endplate currents (EPC) was made with respect to dispersion of quanta secretion and to changes in the exponential decay of miniature endplate currents (τmepc). The relationship between RPC amplitude and τmepc follows a double-exponential curve with τ1= 0.3 ms and τ2 = 6 ms. If the amplitude of fully synchronised EPC is taken as 100%, then the loss of EPC amplitude is already 42% with “physiological” parameters of dispersion (the half-rise and decay constant of distribution of secretion probability = 0.5 ms, τmepc =1 ms). This loss is even more substantial if secretion is more dispersed or miniature endplate currents decay faster.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00196832
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