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  • 1
    Electronic Resource
    Electronic Resource
    Isolation and Structure of Biologically Active Gangliosides from the Sea Cucumber Holothuria pervicax (1998)
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1998 (1998), S. 2519-2525 
    Details
    ISSN: 1434-193X
    Keywords: Glycosphingolipids ; Gangliosides ; Sea cucumber ; Holothuria pervicax ; Neuritogenic activity ; Natural products ; Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Three ganglioside molecular species, HPG-8, HPG-3, and HPG-1, have been obtained from the polar fraction of the chloroform/methanol extract of the sea cucumber Holothuriapervicax. The structures of these gangliosides have been determined on the basis of chemical and spectroscopic evidence. They represent new ganglioside molecular species. HPG-8 is a sulfated monosialo-ganglioside, while HPG-3 and HPG-1 are disialo-gangliosides possessing 2→4-linked tandem-type disialosyl moieties. These three gangliosides qualitative neuritogenic activity toward the rat pheochromocytoma cell line, PC-12 cells.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
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    Paper (German National Licenses)
  • 2
    Electronic Resource
    Electronic Resource
    Isolation and Structure of Biologically Active Glycosphingolipids from the Sea Cucumber Cucumaria echinata (1998)
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1998 (1998), S. 371-378 
    Details
    ISSN: 1434-193X
    Keywords: Glycosphinogolipids ; Cerebrosides ; Gangliosides ; Sea cucumber ; Cucumaria echinata ; Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Five cerebrosides, CE-1-1, CE-1-2, CE-1-3, CE-3-1, and CE-3-2, and a ganglioside molecular species CG-1 have been obtained from the less polar and polar fractions, respectively, of the chloroform/methanol extract of the sea cucumber Cucumaria echinata. The structures of these glycosphingolipids have been determined on the basis of chemical and spectroscopic evidence. The cerebrosides show lethality toward brine shrimps. On the other hand, the ganglioside CG-1 exhibits neuritogenic activity toward the rat pheochromocytoma cell line, PC-12 cells.
    Type of Medium: Electronic Resource
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    Paper (German National Licenses)
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