ISSN:
1432-0878
Keywords:
Adrenal cortex
;
X-zone
;
Zona reticularis
;
Sex steroids
;
Electron microscopic morphometry
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary In the adrenal cortex of 23-to 27-day-old C3H/Tw female mice, the eosinophilic X-zone became increasingly undetectable after 3 injections of 100 μg testosterone propionate (TP). Whorls of smooth endoplasmic reticulum (sER) and peculiar complexes of mitochondria and sER, characteristics of X-zone cell, were no longer present in mice given 7 daily injections of TP. The ordinary mitochondria, although reduced in number, became swollen and actually increased in percent area occupied. They had well-developed tubulovesicular cristae. The lipid droplets increased in size and number after 3 daily TP injections, but decreased after 7 daily injections. Rough endoplasmic reticulum and sER were reduced in area in mice receiving 7 daily injections. The X-zone also became indistinguishable from the zona fasciculata after 7 daily injections of 5α-dihydrotestosterone propionate. Injections of progesterone or estradiol-17β had no effect on the X-zone.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00220393
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