Publication Date:
1986-12-19
Description:
The phosphoinositides are minor phospholipids present in all eukaryotic cells. They are storage forms for messenger molecules that transmit signals across the cell membrane and evoke responses to extracellular agonists. The phosphoinositides break down to liberate messenger molecules or precursors of messenger molecules. Many different compounds are formed, although the functions of only a few are understood. Recent studies elaborating the pathways for formation of products from phosphoinositides and the factors controlling their metabolism are summarized here.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Majerus, P W -- Connolly, T M -- Deckmyn, H -- Ross, T S -- Bross, T E -- Ishii, H -- Bansal, V S -- Wilson, D B -- HL 16634/HL/NHLBI NIH HHS/ -- HLBI 14147/HL/NHLBI NIH HHS/ -- T32 HLBI 07088/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 1986 Dec 19;234(4783):1519-26.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3024320" target="_blank"〉PubMed〈/a〉
Keywords:
Arachidonic Acid
;
Arachidonic Acids/metabolism
;
Cell Division
;
Diglycerides/metabolism
;
Inositol Phosphates/metabolism
;
Phosphatidylinositols/*metabolism
;
Type C Phospholipases/metabolism
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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