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  • 1
    Electronic Resource
    Electronic Resource
    Histone shuttling by poly ADP-ribosylation (1994)
    Springer
    Molecular and cellular biochemistry 138 (1994), S. 53-59 
    Details
    ISSN: 1573-4919
    Keywords: poly(ADP-ribose)polymerase ; poly(ADP-ribose) glycohydrolase ; DNA repair ; chromatin ; nucleosomal unfolding ; NAD+
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract The enzymes poly(ADP-ribose)polymerase and poly(ADP-ribose) glycohydrolase may cooperate to drive a histone shuttle mechanism in chromatin. The mechanism is triggered by binding of the N-terminal zinc-finger domain of the polymerase to DNA strand breaks, which activates the catalytic activities residing in the C-terminal domain. The polymerase converts into a protein carrying multiple ADP-ribose polymers which displace histones from DNA by specifically targeting the histone tails responsible for DNA condensation. As a result, the domains surrounding DNA strand breaks become accessible to other proteins. Poly(ADP0ribose) glycohydrolase attacks ADP-ribose polymers in a specific order and thereby releases histones for reassociation with DNA. Increasing evidence from different model systems suggests that histone shuttling participates in DNA repairin vivo as a catalyst for nucleosomal unfolding.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00928443
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  • 2
    Electronic Resource
    Electronic Resource
    Isolation of 8-methoxypsoralen accessible DNA domains from chromatin of intact cells (1990)
    Springer
    Cell biology and toxicology 6 (1990), S. 35-45 
    Details
    ISSN: 1573-6822
    Keywords: Chromatin organization ; DNA repair ; hepatocytes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: The chromatin organization of living mammalian cells was probed using 8-methoxypsoralen (MOP). In intact cells, MOP intercalates into DNA domains which are also preferentially accessible to micrococcal nuclease. After UV365 nm irradiation of MOP-treated cells, this chemical forms bifunctional adducts crosslinking the two strands of DNA. Following extraction of cellular DNA, heat denaturation and renaturation at low temperature, the fraction of crosslinked DNA is obtained following enzymatic hydrolysis of unhybridized, non-crosslinked DNA ny nuclease S1 treatment. An application of this procedure in the isolation of 8-methoxypsoralen-accessible DNA domains during DNA excision repair is shown.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00135025
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  • 3
    facet.materialart.
    Unknown
    De eerste vondst van de lichtgroene sabelsprinkhaan Metrioptera bicolor in Nederland (Orthoptera: Tettigoniidae) (2004)
    In:  Nederlandse Faunistische Mededelingen vol. 21, pp. 7-10
    Details
    Publication Date: 2024-01-12
    Description: The two-coloured bush-cricket Metrioptera bicolor, first record for the Netherlands\n(Orthoptera: Tettigoniidae)\nThe first record of Metrioptera bicolor for the Netherlands is presented. A long winged male was\nfound singing in a chalk grassland with high vegetation in the Poppelmondedal on the Sint\nPietersberg (southernmost part of the province of Limburg). Recently the species has reached\nclose to the Dutch border in Belgium and Germany. The northward expansion of this highly\nxerothermophilic species is due to a period of warm summers on a row. Whether the species will\nsettle in the Netherlands depends on the climatic conditions.
    Keywords: Sprinkhanen ; Nederland ; Herkenning ; Verspreiding
    Repository Name: National Museum of Natural History, Netherlands
    Type: info:eu-repo/semantics/article
    Format: application/pdf
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  • 4
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    Massaal voorkomen van de sikkelsprinkhaan Pheneroptera falcata op de Oirschotse heide (Orthoptera: Tettigonidae) (2004)
    In:  Nederlandse Faunistische Mededelingen vol. 20, pp. 13-16
    Details
    Publication Date: 2024-01-12
    Description: A large population of the sicklebearing bush-cricket Phaneroptera falcata on the Oirschotse\nHeide (Orthoptera: Tettigoniidae)\nIn 2003 a large population of Phaneroptera falcata was found at the Oirschotse heide, in the\nprovince of Noord-Brabant in the Netherlands. The total number of individuals was estimated\nat 15,000 with a density of approximately 1 specimen per square meter. A large population like\nthis has never been reported for the Netherlands. In the rest of Europe densities of P. falcata\nbetween 0,01 and 0,13 specimens per square meter are reported. The location is a former agricultural\nfield (7 ha) with a rough vegetation dominated by Senecio jacobea and Cirsium arvense.
    Keywords: Sprinkhanen ; Phaneroptera falcata ; Verspreiding ; Nederland
    Repository Name: National Museum of Natural History, Netherlands
    Type: info:eu-repo/semantics/article
    Format: application/pdf
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