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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Lasers in medical science 10 (1995), S. 93-104 
    ISSN: 1435-604X
    Keywords: Copper vapour laser ; Electron microscopy ; Illumination time ; Numerical modelling ; Optimal treatment ; Port-wine stain
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract This paper reports the electron microscopy results obtained from two patients who were treated with 5 W of yellow (578 nm) light from a copper vapour laser with an illumination time of 3.6 ms and a 0.3 mm spot diameter. The endpoint of treatment was transient blanching. Following treatment, erythema was observed. There was minimal damage to the epidermis and non-vascular tissue such as the nerve fibres. There was severe damage to the endothelial cells of the ectatic vessels. Twenty-four hours after treatment, platelet activation and collagen were present, indicating that these vessels were no longer viable. Theoretical calculations are used to determine the flow of heat within and away from a 50μm diameter vessel. From this, heating of the entire vessel is shown to occur with illumination times of 4 ms, with minimal heating of the non-vascular tissue. Shorter illuminations do not heat the entire vessel, while the use of longer illumination times will cause excessive damage to the surrounding non-vascular tissue. Illumination times close to 4 ms must be regarded as optimal.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Lasers in medical science 5 (1990), S. 43-49 
    ISSN: 1435-604X
    Keywords: Copper vapour laser ; Argon ion laser ; Port wine stains ; Telangiectasia ; Spider naevi ; Questionnaire
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract A questionnaire was sent to 242 patients who had undergone treatment with yellow light (578 nm) from a copper vapour laser for a port wine stain (PWS), for facial telangiectasia (FT), or for a spider naevus (SN). The questionnaire covered the social implications of the lesion, the physical appearance of the lesion after treatment and the patient's judgement of how the treatment has affected them. Replies were received from 73% of the patients. The replies revealed that 83% PWS, 74% FT, and 81% SN patients felt there had been an improvement in their appearance compared with 2.5% PWS, 14% FT, and 7.5% SN patients who felt that their appearance had changed for the worse. The overall impression of the treatment was also very positive, especially with PWS patients, 91% would recommend the treatment to others, 84% would have the treatment again and 60% indicated their feelings regarding their overall treatment and the effect it had on their lives was very good.
    Type of Medium: Electronic Resource
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