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  • 1
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    Berlin, Heidelberg : Springer
    Keywords: Chemistry ; Clinical health psychology ; Food science ; Nutrition ; Toxicology
    ISBN: 9783540270034
    Language: English
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Process Safety Progress 14 (1995), S. 266-270 
    ISSN: 1066-8527
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The activation energies of two wood sawdusts were determined using an experimental technique based on the crossing-point temperature concept, which was derived from the transient model of self-heating in a solid. The two samples used in this study were treated and untreated sawdust. The activation energies measured were 106 ± 4 kJ mol-1 for the treated sawdust and 90 ± 3 kJ mol-1 for the untreated sawdust. These values are similar to those in previously published results which were obtained using the steady-state model. The transient model provides a quicker yet sufficiently accurate method of determining thermal ignition kinetics.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 11 (1984), S. 360-366 
    ISSN: 0306-042X
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Mass spectrometric fragmentation of cyclophosphamide (CP) has been studied in detail using linked field scanning, isotope labelling, low energy ionization and accurate mass measurements. The molecular ion is of low abundance and it favours loss of HCI and ·CH2CI to form the base peak at m/z 211. All the other ions are formed by sequential fragmentation processes. The direct bond rupture between phosphorus and the N-chloroethyl group produces two ions m/z 120 and m/z 92. The ion m/z 56 is a triplet. Many of the ions in the spectrum are produced by several competing pathways. Several of the rearrangement mechanisms involve a single hydrogen transfer. Quantitative differences between two commercial CP preparations were observed in the linked field scanning spectra. Differences in the abundances of the metastable ions strongly suggest that there is an intense isomeric competition in the decomposition pathways. The experimental evidence supports the conclusion that the two CP preparations differ in their isomeric composition and these differences are related to their stereoisomers. The rates of the individual fragmentation pathways are dependent upon the isomeric structure of the parent molecule and might also be reflected by different rates of metabolism of the isomers of the drug in vivo.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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