Publication Date:
1999-11-24
Description:
A general approach is presented for creating polymer gels that can recognize and capture a target molecule by multiple-point interaction and that can reversibly change their affinity to the target by more than one order of magnitude. The polymers consist of majority monomers that make the gel reversibly swell and shrink and minority monomers that constitute multiple-point adsorption centers for the target molecule. Multiple-point interaction is experimentally proven by power laws found between the affinity and the concentration of the adsorbing monomers within the gels.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Oya, T -- Enoki, T -- Grosberg, A Y -- Masamune, S -- Sakiyama, T -- Takeoka, Y -- Tanaka, K -- Wang, G -- Yilmaz, Y -- Feld, M S -- Dasari, R -- Tanaka, T -- New York, N.Y. -- Science. 1999 Nov 19;286(5444):1543-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Physics and Center for Materials Science and Engineering, Department of Chemistry, George R. Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. toyo@mit.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10567256" target="_blank"〉PubMed〈/a〉
Keywords:
Adsorption
;
Ammonium Chloride/*chemistry
;
Arylsulfonates/*chemistry
;
Chlorides/chemistry
;
Gels/*chemistry
;
Methacrylates/*chemistry
;
Polymers/*chemistry
;
Spectrometry, Fluorescence
;
Spectrophotometry, Ultraviolet
;
Temperature
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
Permalink
