ALBERT

Description: Introduction: Continuously evolving medical standards of care, limited crew training time, and the inherent constraints of space flight necessitate regular revisions of the mission medical support infrastructure and methodology. A three-day Operational and Research Musculoskeletal Summit was held to review NASA s current strategy for preflight health maintenance and injury screening, risk mitigation for musculoskeletal injuries or syndromes, treatment methods during flight, and research topics to mitigate risks to astronaut health. The Summit also undertook consideration of the best evidence-based terrestrial musculoskeletal practices to recommend their adaptation for use in space. Methods: The types and frequencies of musculoskeletal injuries sustained by short- and long-duration astronauts were obtained from the Longitudinal Study of Astronaut Health. The Summit panel was comprised of experts from the clinical and research communities, as well as representatives from NASA Headquarters, the Astronaut corps, and the offices of JSC Medical Operations, JSC Human Adaptation and Countermeasures, Glenn Research Center Human Research, and Astronaut Strength Conditioning and Rehabilitation. Before the summit, panelists participated in a Web-based review of NASA s Space Medical Conditions List (SMCL). Results: The Summit generated seventy-five operational and research recommendations to the NASA Office of Space Medicine, including changes to the SMCL and to the musculoskeletal section of the ISS debrief questionnaire. From these recommendations, seven were assigned highest value and priority, and could be immediately adopted for the exploration architecture. Discussion: Optimized exercise and conditioning to improve performance and forestall musculoskeletal damage on orbit were the primary area of focus. Special attention was paid to exercise timing and muscle group specificity. The panel s recommendations are currently in various stages of consideration or integration into the ISS and Exploration programs. This effort serves to enhance the on-orbit system so comprehensive treatment can be delivered in a more effective and standardized manner.

Description: OBJECTIVES: The risk of a urinary calculus during an extended duration mission into the reduced gravity environment of space is significant. For medical operations to develop a comprehensive strategy for the spaceflight stone risk, both preventive countermeasures and contingency management (CM) plans must be included. METHODS: A feasibility study was conducted to demonstrate the potential CM technique of endoscopic ureteral stenting with ultrasound guidance for the possible in-flight urinary calculus contingency. The procedure employed the International Space Station/Human Research Facility ultrasound unit for guide wire and stent localization, a flexible cystoscope for visual guidance, and banded, biocompatible soft ureteral stents to successfully stent porcine ureters bilaterally in zero gravity (0g). RESULTS: The study demonstrated that downlinked endoscopic surgical and ultrasound images obtained in 0g are comparable in quality to 1g images, and therefore are useful for diagnostic clinical utility via telemedicine transmission. CONCLUSIONS: In order to be successful, surgical procedures in 0g require excellent positional stability of the operating surgeon, assistant, and patient, relative to one another. The technological development of medical procedures for long-duration spaceflight contingencies may lead to improved terrestrial patient care methodology and subsequently reduced morbidity.

Description: In response to the question 'what to do next' at Mars we explore the value of a high precision in situ measurement of isotopic and trace gas constituents in the atmosphere combined with a similar analysis of gas extracted from near surface rocks and soils. The scientific goals are to advance our understanding of the evolution of the Martian atmosphere and to search for fossils of past geochemical conditions. One element of this program that ties directly to the goals of the Astrobiology Program will be a sensitive search for simple or complex organic molecules contained in the atmosphere and in the solid phase. The broad chemical and isotopic analysis planned insures that a highly successful program will be carried out even if no organics are detected. We will demonstrate that the technology to carry out this Program is presently in hand.

Description: A sample return mission is an important next step in the exploration of Mars. The first sample return should come early in the program time-line because the science derived from earth-based analyses of samples provides crucial "ground truth" needed for further exploration planning, enhancement of remote measurements, and achieving science goals and objectives that include: (1) the search for environments that may support life and any indicators of the past or present existence of life, (2) understanding the history of water and climate on Mars, (3) understanding the evolution of Mars as a planet. Returned samples from Mars will have unique value because they can be studied by scientists worldwide using the most powerful analytical instruments available. Furthermore, returned Mars samples can be preserved for studies by future generations of scientists using new techniques and addressing new issues in Mars science. To ensure a high likelihood of success, the first sample return strategy should be simple and focused. We outline a fundamental set of sample requirements and acquisition priorities for Mars sample return.

Description: The martian mantle is apparently heterogeneous, which opens the possibility that it is layered, with each layer convectively isolated. If this is correct, melt generation should occur either at thermal boundary layers or in plumes generated at those boundaries. Mantle layering may be a good means of slowing the planet's cooling rate, allowing young volcanism. Layering may also provide a means for keeping the crust and upper mantle cool, allowing the preservation of ancient variations in crustal thickness.

Description: The SNC (martian) meteorites exhibit complex isotopic characteristics that yield information both about the ages of individual meteorites as well as information about the petrogenetic processes that produced both individual samples and about the origins of suites and sub-suites within the SNC clan. Here I review these data, reiterate earlier interpretations, and offer some new conclusions.

Description: Tumbleweed is a wind-propelled long-range vehicle based on well-developed and tested technology, instrumented to perform surveys Mars analog environments for habitability and suitable for a variety of missions on Mars. Tumbleweeds are light-weight and relatively inexpensive, making it very attractive for multiple deployments or piggy-backing on a larger mission. Tumbleweeds with rigid structures are also being developed for similar applications. Modeling and testing have shown that a 6 meter diameter Tumbleweed is capable of climbing 25 hills, traveling over 1 meter diameter boulders, and ranging over a thousand kilometers. Tumbleweeds have a potential payload capability of about 10 kilograms with approximately 10-20 Watts of power. Stopping for science investigations can also be accomplished using partial deflation or other braking mechanisms. Surveys for Astrobiology and other applications of tumbleweeds are shown.

Description: We peformed a series of metal/silicate partitioning thought experiments where contamination of the silicate by metal increases as the size of the charge decreases. Unfortunately, regression of this entirely artificial dataset leads to very reasonable result.

Description: Results from an experimental deformation study on natural chondrite demonstrate Fe-Ni-O-S liquid mobility, and its resulting geochemical signature, within a solid silicate matrix under low temperature (900-1000 C) and high stress conditions.

Description: Measured and calculated Nd and Hf isotopic compositions for geochemical reservoirs on the Moon and Mars are strikingly similar in some instances. Consequently, a magma ocean model is favored for Mars as well as the Moon.