ISSN:
1573-8221
Keywords:
superoxide dismutase
;
1,4-diazobicyclo[2.2.2]octane
;
catalase
;
singlet oxygen
;
hyperoxia
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract A single intravenous injection of a purified preparation of superoxide dismutase (1000 units) simultaneously with catalase (0.5 mg) or without it into mice did not protect the animals against the toxic action of 100% oxygen under a pressure of 5 atm. Intraperitoneal injection of 1,4-diazobicyclo[2.2.2]octane (6 mg) under these conditions prolonged the preconvulsive period and increased the survival rate of the mice. It is suggested that singlet oxygen is formed during hyperoxia.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00799403
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