Publication Date:
2018-11-17
Description:
A hPSC-based platform to discover gene-environment interactions that impact human β-cell and dopamine neuron survival A hPSC-based platform to discover gene-environment interactions that impact human β-cell and dopamine neuron survival, Published online: 16 November 2018; doi:10.1038/s41467-018-07201-1 Diseases such as diabetes and Parkinson's manifest based on interactions between genes and environment. Here, the authors find among a panel of cell types that propargite, a common pesticide, induces pancreatic β-cell and dopamine neuron death and that loss of the gene GSTT1 confers hypersensitivity.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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