Publication Date:
2015-04-25
Description:
Article Rearrangements of the Ig loci are essential for generating antibody diversity but abnormal translocations can be a driving event for myeloma. Here Walker et al . perform whole exome sequencing on myeloma patients to capture the diversity of mutational changes. Nature Communications doi: 10.1038/ncomms7997 Authors: Brian A. Walker, Christopher P. Wardell, Alex Murison, Eileen M. Boyle, Dil B. Begum, Nasrin M. Dahir, Paula Z. Proszek, Lorenzo Melchor, Charlotte Pawlyn, Martin F. Kaiser, David C. Johnson, Ya-Wei Qiang, John R. Jones, David A. Cairns, Walter M. Gregory, Roger G. Owen, Gordon Cook, Mark T. Drayson, Graham H. Jackson, Faith E. Davies, Gareth J. Morgan
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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