ISSN:
1432-072X
Keywords:
Biotransformation
;
Toxicity
;
1-Methylnaphthalene
;
2-Methylnaphthalene
;
1-Hydroxymethylnaphthalene
;
2-Hydroxymethylnaphthalene
;
Cyanobacteria
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract Agmenellum quadruplicatum strain PR-6, Oscillatoria sp. strain JCM and Anabaena sp., strain CA grown photoautotrophically in the presence of either 1- or 2-methylnaphthalene oxidized both compounds at the methyl group to form 1-hydroxymethylnaphthalene and 2-hydroxymethylnaphthalene, respectively. Ring hydroxylated metabolites were not detected. The metabolites were isolated by thin-layer, high performance liquid and gas chromatography and identified by comparison of chromatographic and mass spectral properties with those of authentic compounds. The extent of 1- and 2-methylnaphthalene metabolism to ethyl acetate soluble metabolites ranged from 0.7 to 3.2%. Incubation of Agmenellum quadruplicatum strain PR-6 with 2-methylnaphthalene and molecular oxygen-18 led to the isolation of 2-hydroxymethylnaphthalene that contained oxygen-18. The toxicity of naphthalene, 1- and 2-methylnaphthalene and their derivatives on the growth of Agmenellum quadruplicatum strain PR-6 was investigated using the algal lawn technique. Phenol and quinone derivatives of naphthalene, 1- and 2-methylnaphthalene were most inhibitory. Alkyl side chain hydroxylation products, such as the hydroxymethyl derivatives of 1- and 2-methylnaphthalene were more toxic than the parent methylnaphthalenes. 1- and 2-Naphthoic were not toxic to the cyanobacterium.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00409840
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