ISSN:
1399-0047
Source:
Crystallography Journals Online : IUCR Backfile Archive 1948-2001
Topics:
Chemistry and Pharmacology
,
Geosciences
,
Physics
Notes:
Transcobalamin is a cobalamin-binding protein in mammalian plasma that facilitates the cellular uptake of vitamin B12. Human transcobalamin was crystallized using polyethylene glycol and ethanol as precipitants. Crystals belong to the orthorhombic space group P212121, with unit-cell parameters a = 49.04, b = 145.27, c = 164.96 Å. A complete data set to 3.2 Å resolution was collected from a single crystal using synchrotron radiation. Estimation of the crystal packing (VM = 3.2 Å3 Da−1) and self-rotation function analysis suggest the presence of two molecules in the asymmetric unit related by non-crystallographic twofold symmetry.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1107/S0907444901015360
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