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  • 1
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    Multiview Translation Learning for Knowledge Graph Embedding (2020)
    Hindawi
    Details
    Publication Date: 2020-08-25
    Description: Recently, knowledge graph embedding methods have attracted numerous researchers’ interest due to their outstanding effectiveness and robustness in knowledge representation. However, there are still some limitations in the existing methods. On the one hand, translation-based representation models focus on conceiving translation principles to represent knowledge from a global perspective, while they fail to learn various types of relational facts discriminatively. It is prone to make the entity congestion of complex relational facts in the embedding space reducing the precision of representation vectors associating with entities. On the other hand, parallel subgraphs extracted from the original graph are used to learn local relational facts discriminatively. However, it probably causes the relational fact damage of the original knowledge graph to some degree during the subgraph extraction. Thus, previous methods are unable to learn local and global knowledge representation uniformly. To that end, we propose a multiview translation learning model, named MvTransE, which learns relational facts from global-view and local-view perspectives, respectively. Specifically, we first construct multiple parallel subgraphs from an original knowledge graph by considering entity semantic and structural features simultaneously. Then, we embed the original graph and construct subgraphs into the corresponding global and local feature spaces. Finally, we propose a multiview fusion strategy to integrate multiview representations of relational facts. Extensive experiments on four public datasets demonstrate the superiority of our model in knowledge graph representation tasks compared to state-of-the-art methods.
    Print ISSN: 1058-9244
    Electronic ISSN: 1875-919X
    Topics: Computer Science , Media Resources and Communication Sciences, Journalism
    Published by Hindawi
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  • 2
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    New Analysis Theory and Method for Drag and Torque Based on Full-Hole System Dynamics in Highly Deviated Well (2015)
    Hindawi
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    Publication Date: 2015-05-20
    Description: The research on calculation of torque and drag in highly deviated wells has demonstrated a significant gap against oil exploration and development; with the increasingly rigorous situation, the drill string dynamics and the contact or friction of drill pipe with borehole wall under the drill string action of dynamic need more attention and urgent research work. Based on full-hole system dynamics, three-dimensional nonlinear dynamic model and dynamic torque and drag model were established in highly deviated well by using the finite element method. An application of analyzing typical torque and drag problems presented here provides a means to more accurate description of the contact relation between drill string and wellbore. The results show that those models established in this paper have complete adaptability for a complex three-dimensional borehole trajectory. For the actual well application, it will help to evaluate security performance of drill string in complex working conditions.
    Print ISSN: 1024-123X
    Electronic ISSN: 1563-5147
    Topics: Mathematics , Technology
    Published by Hindawi
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  • 3
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    Individual cylinder air–fuel ratio estimation and control for a large-bore gas fuel engine (2019)
    Hindawi
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    Publication Date: 2019
    Description: International Journal of Distributed Sensor Networks, Volume 15, Issue 2, February 2019. 〈br/〉
    Print ISSN: 1550-1477
    Electronic ISSN: 1550-1477
    Topics: Electrical Engineering, Measurement and Control Technology
    Published by Hindawi
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  • 4
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    Effects of the Grain Size on Dynamic Capillary Pressure and the Modified Green–Ampt Model for Infiltration (2018)
    Hindawi
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    Publication Date: 2018-08-26
    Print ISSN: 1468-8115
    Electronic ISSN: 1468-8123
    Topics: Geosciences
    Published by Hindawi
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  • 5
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    Dynamic Analysis for Lateral Vibrations of Footbridges under Crowd Based on a Two-Degrees-of-Freedom Model (2019)
    Hindawi
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    Publication Date: 2019-02-18
    Description: Nakamura’s model is widely used to describe lateral vibrations of a footbridge induced by crowd. The predicted responses of Nakamura’s model were compared with measured data of T-bridge and M-bridge in Japan to demonstrate the validity. However, the predicted responses based on Nakamura’s model almost always were stronger than measured data. Considering that both T-bridge and M-bridge are cable-stayed bridges, it seems to be not precise enough to simplify a cable-stayed bridge as a single degree of freedom system in Nakamura’s model. In this paper, we establish a two-degrees-of-freedom model to describe lateral vibrations of a cable-stayed bridge. The cables have one degree, and the bridge deck has the other. Additionally, in this model we introduce a time delay in interaction between the bridge and pedestrians. By employing the center manifold theory, we find that a subcritical Hopf bifurcation occurs in the two-degrees-of-freedom model. We theoretically and numerically illustrate that the cables and time delay have significant influence on the lateral vibration amplitude of a footbridge under crowd. The appropriate increases of tension in the cables and time delay both can decrease the lateral vibration amplitude. The analysis for the proposed two-degrees-of-freedom model shows that the predicted responses of Nakamura’s model can better agree with the measured date if we take the influence of cables and time delay into account.
    Print ISSN: 1024-123X
    Electronic ISSN: 1563-5147
    Topics: Mathematics , Technology
    Published by Hindawi
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  • 6
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    Wideband Circularly Polarized Ellipse Antenna Array with Gain Enhancement (2018)
    Hindawi
    Details
    Publication Date: 2018-09-17
    Description: In this paper, a wideband circularly polarized (CP) antenna element and array with gain enhancement are presented. The original antenna element adopts two orthogonal ellipse dipoles with end-loading pillars. In order to achieve a wide impedance bandwidth (IBW), a harpoon-shaped feed patch (HSFP) as electromagnetic coupling-feed is utilized. By introducing a coupled frame and a loop cavity, the gain of the element is crucially improved. Then, four sequentially rotated elements placed in a circular contour act as 2 × 2 array, and a similar loop metal cavity is employed to the array to reach gain enhancement. For the wideband CP performance of the proposed antenna, a wideband phase shifting feed network (WPSFN) is used to construct the antenna. Finally, to verify the feasibility of the proposed antenna, a prototype array is manufactured and measured. Experimental results are found in acceptable agreement with the simulated ones in terms of gain, radiation efficiency, radiation pattern, reflection coefficient, and axial ratio (AR). The result indicates that the proposed antenna has an IBW for reflection coefficient S11 ≤ − 10 dB of 85.7% (0.80–2.00 GHz). Moreover, benefit from the sequentially rotated technique (SRT), the AR at broadside direction keeps blow 3 dB during the overlapped bandwidth of S11≤ − 10 dB, and the ARBW for AR ≤ 1 dB of 74.4% (0.85–1.78 GHz) can be achieved. By employing the loop cavity, the right hand circularly polarization (RHCP) gain is significantly improved, which keeps above 10.00 dBic from 1.05 GHz to 1.85 GHz, and the peak gain reaches to 13.91 dBic.
    Print ISSN: 1687-5869
    Electronic ISSN: 1687-5877
    Topics: Electrical Engineering, Measurement and Control Technology
    Published by Hindawi
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  • 7
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    The Protein Expression of PDL1 Is Highly Correlated with Those of eIF2α and ATF4 in Lung Cancer (2018)
    Hindawi
    Details
    Publication Date: 2018-09-16
    Description: Introduction. The expression of programmed death 1 (PD1) and programmed death ligand 1 (PDL1) can be induced by the interferon (IFN)/signal transducer and activator of transcription (STAT) pathway. The PD1/PDL1 reverse signaling can activate the eukaryotic translation initiation factor 2 (eIF2α)/activating transcription factor 4 (ATF4) pathway which in turn regulates the expression of IFN regulatory factor (IRF) 7 and IFNα. The eIF2α/ATF4 pathway is responsible for the integrated stress response (ISR) of unfolded protein response (UPR) which can affect immune cell function in tumor microenvironment. Materials and Methods. The protein levels of PDL1, IRF1, IRF7, STAT1, STAT2, IFNAR1, eIF2α, and ATF4 in the normal and tumor tissues of 27 subjects with lung cancer were determined by Western blot. Results. The protein level of PDL1 was significantly correlated with those of IRF1, eIF2α, and ATF4 in the tissues of all subjects and the subgroup of squamous cell carcinoma but not in the normal tissue of adenocarcinoma. The protein levels of IRF1, eIF2α, and ATF4 were consistently correlated in the tumor tissues but to various extents in the normal ones. The protein level of PDL1 was not correlated with those of STAT1 and STAT2 in all the tissues. Conclusion. The PDL1 expression in lung cancer may be independent of STAT1 and STAT2. The PD1/PDL1 axis and UPR/ISR may be closely associated in the tumor tissues of lung cancer.
    Print ISSN: 0278-0240
    Electronic ISSN: 1875-8630
    Topics: Biology , Chemistry and Pharmacology
    Published by Hindawi
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  • 8
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    The Ratio of Hmox1/Nrf2 mRNA Level in the Tumor Tissue Is a Predictor of Distant Metastasis in Colorectal Cancer (2016)
    Hindawi
    Details
    Publication Date: 2016-01-01
    Description: Heme oxygenase 1 (Hmox1) plays an important role in the growth and spread of tumor, and its expression is regulated positively by Nrf2 [nuclear factor (erythroid-derived 2)-like 2; NFE2L2] and negatively by kelch-like ECH-associated protein 1 (Keap1) and by BTB and CNC homology 1 (Bach1). Both Hmox1 and Nrf2 contribute to distant metastasis of cancer. The mRNA levels of Hmox1, Nrf2, Keap1, and Bach1 in the tumor and normal tissues of 84 subjects with colorectal cancer (CRC) were determined by real-time polymerase chain reaction. The tumor had lower Hmox1 but higher Bach1 mRNA levels than the normal tissue. The correlations of Hmox1 with components of the Nrf2 pathway were not significant in the tumor tissue of CRC subjects with distant metastasis. The ratio of Hmox1/Nrf2 mRNA level (by percentage) in the tumor tissue was lower in the subjects with distant metastasis (97.4% (84.4–111.1%)) than in those without (101.0% (92.7–136.5%)) and was a predictor for distant metastasis in CRC (odds ratio: 0.83; 95% confidence interval: 0.68–0.97) along with serum carcinoembryonic antigen (1.0027, 1.006–1.064). The mRNA level of Hmox1 in the tumor tissue of CRC is not correlated with that of the Nrf2 pathway molecules, and its ratio to the Nrf2 level may be useful for suggesting distant metastasis in CRC.
    Print ISSN: 0278-0240
    Electronic ISSN: 1875-8630
    Topics: Biology , Chemistry and Pharmacology
    Published by Hindawi
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  • 9
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    Functional Haplotypes in the Promoter Region of Transcription FactorNrf2in Chronic Obstructive Pulmonary Disease (2010)
    Hindawi
    Details
    Publication Date: 2010-01-01
    Description: Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) protects against oxidative stress which is important in the pathogenesis of chronic obstructive pulmonary disease (COPD). Three single nucleotide polymorphisms and 1 triplet repeat polymorphism are found in the promoter region of theNrf2gene. Molecular haplotyping of theNrf2promoter region was performed using DNA obtained from the peripheral blood of 69 COPD patients. The luciferase activities ofNrf2promoter constructs containing all possible combinations of the 4 polymorphisms were determined and found to differ among the 16 haplotypes.The haplotypes isolated from the subjects were divided into 3 groups (L: low; M: medium; H: high) on the basis of luciferase activities. The proportions of subjects belonging to global initiative for chronic obstructive lung disease stage 3 or 4 decreased from the group with the LL haplotype to that with the HH haplotype. Presence of the LH or MM haplotype (hazard ratio, 3.36; 95% confidence interval, 1.16–9.69), gender (0.13; 0.02–0.67), and post-bronchodilator FEV1value of predicted (0.95; 0.91–0.99) are significant predictors of respiratory failure development.The haplotype of theNrf2gene promoter affects its activity, and is associated with the severity and the development of respiratory failure in COPD.
    Print ISSN: 0278-0240
    Electronic ISSN: 1875-8630
    Topics: Biology , Chemistry and Pharmacology
    Published by Hindawi
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  • 10
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    An Inverted Pendulum Model Describing the Lateral Pedestrian-Footbridge Interaction (2018)
    Hindawi
    Details
    Publication Date: 2018-11-01
    Description: In this paper, the lateral pedestrian-footbridge interaction is investigated by using the model of an inverted pendulum on a cart. The inverted pendulum and the cart separately represent the synchronous pedestrians and the footbridge. The pivot point of the inverted pendulum is considered to vibrate harmonically to model the walking motion of the pedestrians. The proposed inverted pendulum model avoids the difficulty of the determination of the lateral force induced by the pedestrians applying to the footbridge, which was usually treated based on a semiempirical approach in previous works. Moreover, the model can describe the whole process: how the lateral amplitude of the bridge increases from small to large. Measurement data showed that a normal pedestrian always keeps the ratio of 1/2 between the lateral and vertical step frequencies. The theoretical analysis for the inverted pendulum model indicates that such walking habit of pedestrians is the root of the frequency-locking phenomenon, which eventually results in excessive lateral vibrations of the bridge. Furthermore, such walking habit also is a key factor in the occurrence of the “jump phenomenon” in the London Millennium Bridge.
    Print ISSN: 1687-8086
    Electronic ISSN: 1687-8094
    Topics: Architecture, Civil Engineering, Surveying
    Published by Hindawi
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