Publication Date:
2017-05-04
Description:
Assembly of functionally integrated human forebrain spheroids Nature 545, 7652 (2017). doi:10.1038/nature22330 Authors: Fikri Birey, Jimena Andersen, Christopher D. Makinson, Saiful Islam, Wu Wei, Nina Huber, H. Christina Fan, Kimberly R. Cordes Metzler, Georgia Panagiotakos, Nicholas Thom, Nancy A. O’Rourke, Lars M. Steinmetz, Jonathan A. Bernstein, Joachim Hallmayer, John R. Huguenard & Sergiu P. Paşca The development of the nervous system involves a coordinated succession of events including the migration of GABAergic (γ-aminobutyric-acid-releasing) neurons from ventral to dorsal forebrain and their integration into cortical circuits. However, these interregional interactions have not yet been modelled with human cells. Here we generate
Print ISSN:
0028-0836
Electronic ISSN:
1476-4687
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics
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