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  • 1
    Publication Date: 2008-10-01
    Description: Reliability-based design concepts and their application to load and resistance factor design (LRFD or limit states design (LSD) in Canada) are well known, and their adoption in geotechnical engineering design is now recommended for many soil–structure interaction problems. Two important challenges for acceptance of LRFD for the design of reinforced soil walls are (i) a proper understanding of the calibration methods used to arrive at load and resistance factors, and (ii) the proper interpretation of the data required to carry out this process. This paper presents LRFD calibration principles and traces the steps required to arrive at load and resistance factors using closed-form solutions for one typical limit state, namely pullout of steel reinforcement elements in the anchorage zone of a reinforced soil wall. A unique feature of this paper is that measured load and resistance values from a database of case histories are used to develop the statistical parameters in the examples. The paper also addresses issues related to the influence of outliers in the datasets and possible dependencies between variables that can have an important influence on the results of calibration.
    Print ISSN: 0008-3674
    Electronic ISSN: 1208-6010
    Topics: Geosciences
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  • 2
    Publication Date: 2020-12-01
    Description: The aim of this paper is to propose a new non-invasive methodology to estimate thermogenesis in newborns with perinatal asphyxia (PA) undergoing therapeutic hypothermia (TH). Metabolic heat production (with respect to either a neonate’s body mass or its body surface) is calculated from the newborn’s heat balance, estimating all remaining terms of this heat balance utilising results of only non-invasive thermal measurements. The measurement devices work with standard equipment used for therapeutic hypothermia and are equipped with the Global System for Mobile Communications (GSM), which allows one to record and monitor the course of the therapy remotely (using an internet browser) without disturbing the medical personnel. This methodology allows one to estimate thermogenesis in newborns with perinatal asphyxia undergoing therapeutic hypothermia. It also offers information about instantaneous values of the rate of cooling together with values of remaining rates of heat transfer. It also shows the trend of any changes, which are recorded during treatment. Having information about all components of the heat balance one is able to facilitate comparison of results obtained for different patients, in whom these components may differ. The proposed method can be a new tool for measuring heat balance with the possibility of offering better predictions regarding short-term neurologic outcomes and tailored management in newborns treated by TH.
    Electronic ISSN: 2045-2322
    Topics: Natural Sciences in General
    Published by Springer Nature
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