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The Aspergillus niger acuA and acuB genes correspond to the facA and facB genes in Aspergillus nidulans (1999)

Papadopoulou, Stella ; Sealy-Lewis, Heather M

Oxford, UK : Blackwell Publishing Ltd

FEMS microbiology letters 178 (1999), S. 0

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ISSN: 1574-6968

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Biology

Notes: Mutants in Aspergillus niger unable to grow on acetate as a sole carbon source were previously isolated by resistance to 1.2% propionate medium containing 0.1% glucose. AcuA mutants lacked acetyl-CoA synthetase (ACS) activity and acuB mutants lacked both ACS and isocitrate lyase activity. An acuA mutant was transformed to the acu+ phenotype with a clone of ACS (facA) from Aspergillus nidulans. The acuB mutant was transformed with the A. niger facB clone which has been identified by cross-hybridisation of an A. nidulans facB clone. These results confirm that acuA in A. niger is the gene for ACS and acuB is analogous to the A. nidulans facB regulatory gene.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1574-6968.1999.tb13756.x

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