ISSN:
1574-6968
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Biology
Notes:
Abstract The majority of methicillin-resistant Staphylococcus aureus isolated in Australia since 1980 carries a determinant encoding resistance to a variety of nucleic acid-binding (NAB) compounds, including ethidium bromide (EB) acriflavine and propamidine isothionate. In addition, an EB-resistance determinant is frequently located on conjugative plasmids encoding aminoglycoside resistance. A comparison of these two determinants revealed that the EB-resistance determinant also encoded resistance to several NAB compounds. However, the NAB- and the EB-resistance determinants differed in both the number of NAB-compounds to which they expressed resistance, and the level of resistance expressed towards these compounds. Whilst these 2 determinants have several features in common, the results suggest that the NAB- and EB-resistance determinants are not identical.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1574-6968.1985.tb01639.x
Permalink
