ISSN:
1432-1351
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary Acute experiments in chickens demonstrated that glucagon inhibited the volume of spontaneous gastric juice secretion (proventriculus-gizzard) with a corresponding decrease in pepsin output. Glucagon did slightly reduce the volume of histamine-stimulated gastric juice, but the pepsin secretion decreased by 50%. The pentagastrin stimulatory effect on gastric secretion was suppressed by glucagon. The effect of glucagon on the proventriculus in chickens is very similar to its effect on gastric secretion in mammals. The amylase concentration of basal duodenal secretion showed variations, being high at the beginning of the experimental period, decreasing subsequently, with a tendency to increase in later periods. No parallelism between the volume of duodenal juice and amylase levels could be established. Glucagon inhibited the basal duodenal juice flow. After 60 min of suppression, the secretory activity returned to its basal level. The duodenal secretory activity is not affected by histamine. Glucagon following histamine inhibited the secretory activity of the Lieberkühn glands, like basal secretion. Pentagastrin slightly stimulated duodenal secretion. Glucagon inhibited the pentagastrin action on duodenal secretion. The effect of glucagon on the Lieberkühn glands in the chicken is just the opposite of that on Brunner glands secretion in dogs.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00297731
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