ISSN:
1476-4687
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics
Notes:
[Auszug] In preparation for base sequencing, 300-nucleotide repeated sequences are liberated from renatured human DNA (Cot = 68) by S1 nuclease digestion4. These 300-nucleotide duplex fragments are presumed to have frayed single strand ends which would be unsuitable for base sequencing (Fig. 1a). To ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/284372a0
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