ISSN:
1040-7685
Keywords:
open tubular liquid chromatography
;
injection systems
;
profile factors
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The main advantages of open tubular liquid chromatography (OTLC) over conventional packed-column liquid chromatography are the gain in resolution and the increased permeability. At present the reproducible preparation of narrow-bore columns and the lack of suitable commercial chromatographic equipment delay the development of OTLC. There are stringent requirements for injectors and detectors for OTLC with respect to their volumes, geometry, and contributions to the total band broadening. In this work some properties of two different sampling systems for OTLC were studied with respect to the accuracy and repeatability of the injected volumes. An approach is presented and discussed to determine the profile factors of these injection systems.
Additional Material:
3 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mcs.1220020309
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