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  • Chemistry  (2)
  • complement fixation  (1)
  • 1990-1994  (2)
  • 1965-1969  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Review of human and animal cases of coccidioidomycosis diagnosed in Canada (1991)
    Springer
    Mycopathologia 113 (1991), S. 1-10 
    Details
    ISSN: 1573-0832
    Keywords: Coccidioidomycosis ; Coccidioides immitis ; pulmonary ; systemic ; cutaneous ; micro-immunodiffusion ; complement fixation ; human ; animal ; distrubution
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The first Canadian case of coccidioidomycosis in a human was reported in 1952 and 11 more cases since then. This study provides details of other cases of coccidioidomycosis that have been diagnosed in Canada. Based on clinical details, isolation of Coccidioides immitis, detection of a specific antibody (F band) for coccidioidomycosis by macro- or microimmunodiffusion tests, concurrently used with the complement fixation procedure, and histopathological findings, 116 more cases of this disease were verified. The great majority (94%) of these cases were diagnosed in the western Canadian provinces of British Columbia, Alberta, Saskatchewan and Manitoba, and the others in Quebec, Ontario and Nova Scotia (5,1, and 1 cases, respectively). Available information indicates that the C. immitis infections were contracted during visits to endemic areas in the United States (Arizona, California and New Mexico), Mexico, and Bolivia. Pulmonary infections were the most common type of coccidioidomycosis (93%) followed by the disseminated or meningeal types C. immitis infections occurred in individuals with or without predisposing factor(s) and were more common in males than in females. The exoantigen procedure was very useful and reliable in the accurate and rapid identification of suspected C. immitis isolates. Two cases of coccidioidomycosis were reported in animals in Ontario, Canada.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00436377
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  • 2
    Electronic Resource
    Electronic Resource
    The motion of algae in turbulent flow (1965)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 7 (1965), S. 295-308 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Large cultures of microscopic, unicellular algae have been proposed as a means of maintaining a life-supporting atmosphere in a closed, manned system. To achieve vigorous growth of the algal culture it is necessary to subject individual algae alternately to short periods of high intensity light and darkness. One of the means suggested for obtaining a favorable light-dark sequence for photosynthesis is to cause turbulence in a closed channel on which light is incident. Since light is rapidly attenuated in a dense suspension, there will be illuminated regions adjacent to the channel walls and a dark central core. The random motions of turbulence normal to the direction of flow would move the algae alternately from the illuminated regions to the dark region and back again. This paper indicates a method for analyzing the motion of algae into and out of the illuminated region of a channel formed by flat, parallel, transparent plates, with light incident on the plates. Matching of a probability model with a diffusion model makes it possible to estimate the light-dark sequence which could be achieved by turbulence. The results indicate that favorable sequences by this mechanism are unlikely.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260070209
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  • 3
    Electronic Resource
    Electronic Resource
    Application of the distance geometry algorithm to cyclic oligopeptide conformation searches (1990)
    New York : Wiley-Blackwell
    Biopolymers 30 (1990), S. 45-56 
    Details
    ISSN: 0006-3525
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The distance geometry algorithm as embodied in the program DGEOM was examined as a method for searching cyclic peptide conformations. Conformations were randomly generated using covalent distance and chirality constraints, but torsion angle rather than distance sampling was used for 1, 4 relationships. Structures so generated were energy minimized by a fixed number of iterations using the molecular mechanics program AMBER 3.0; electrostatic terms were excluded in the minimization. The effectiveness of this procedure in sampling conformational space for cyclic peptides was measured by the ability to recover, from a set of 500 structures, conformations similar to those experimentally observed for six cyclic peptides containing from 8 to 20 rotatable backbone bonds. Structures similar to experimental structures were recovered in a 16-bond case, but not for a 20-bond example. The method was also applied, with constraints on the peptide bond angles ω, to an additional example containing 21 ring bonds.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bip.360300107
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