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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Industrial & engineering chemistry research 34 (1995), S. 2898-2909 
    ISSN: 1520-5045
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Ground water 37 (1999), S. 0 
    ISSN: 1745-6584
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Geosciences
    Notes: A spatial stochastic approach was adopted to estimate the capture zones of a welifield in eastern Netherlands near the town of Wierden. The main sources of uncertainty were found to be the hydraulic conductivity of the production aquifer and the spatial distribution and thickness of an impeding clay layer situated above the production aquifer. Both were modeled as random space functions and a Monte Carlo analysis was performed to assess the probability distributions of the capture zones for t = 25 years and t →∞. The distributions were compared with two deterministic capture zones to show how the stochastic approach preserves the discontinuous character of the impeding clay layer while the deterministic approach smooths out the discontinuities. Furthermore, it is shown how the stochastic approach reveals the uncertainty about the location of the capture zones while the deterministic approach obscures it.
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  • 3
    ISSN: 1546-1718
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Holt-Oram syndrome is characterized by upper limb malformations and cardiac septation defects. Here, we demonstrate that mutations in the human TBX5 gene underlie this disorder. TBX5 was cloned from the disease locus on human chromosome 12q24.1 and identified as a member of the T-box transcription ...
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  • 4
    ISSN: 1572-879X
    Keywords: N2O decomposition ; calcined HTlc's ; cobalt spinel ; palladium ; rhodium ; lanthanum ; magnesium aluminate ; Mg stabilization ; SO2 poisoning
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The catalytic decomposition of nitrous oxide to nitrogen and oxygen has been studied over calcined hydrotalcite‐like compounds containing different combinations of bivalent (Co, Pd, Mg) and trivalent (Al, La, Rh) cations with carbonate as interlayer anion. The precursors were prepared by co‐precipitation under low supersaturation conditions and characterized by XRD and TG/DSC. The mixed oxides derived after calcination at 723 K were characterized by XRD, N2 adsorption at 77 K, and XRF. The presence of Rh, La, or Pd in the Co‐based HTlc's improves considerably the catalytic activity. Co–Rh,Al‐HTlc (Co/Rh/Al==3/0.02/1) proved to be a very active catalyst, although the presence of the noble metal Pd in this catalyst ex‐Co,Pd–La,Al‐HT (Co/Pd/La/Al=3/1/1/1) produces a similar catalytic activity to that of Rh‐containing catalyst, both in a N2O‐containing stream and in one containing also SO2 and O2, but with a better performance in stability tests. PdO phase has been identified by XRD as being responsible for the considerable improvement in the activity. The presence of Mg as spinel structure exerts a stabilizing effect in the more active catalysts when mixtures of SO2 and O2 are considered.
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  • 5
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 239-241 (Nov. 1996), p. 283-286 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Electrical engineering 81 (1998), S. 151-161 
    ISSN: 1432-0487
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Description / Table of Contents: Contents The spectrum of the magnetic field in the air gap of induction motors is influenced by the level of saturation of the magnetic circuit. This report deals with the effects of saturation, which are significantly different in case of yoke respectively teeth saturation. The research is done by means of numerical field calculations of a simplified model. The results are compared with a commonly used analytical approach. Beside of the reduction of the fundamental field the effects of saturation on the third and fifth space-harmonics are found to be most important. The effect on the slot harmonics is proved to be negligible for the model presented.
    Notes: Übersicht Das Spektrum des Luftspaltfelds ändert sich unter dem Einfluß der Sättigung der Eisenbereiche. Anhand numerischer Feldberechnungen wird gezeigt, daβ zwischen der Sättigung im Zahn- und Jochbereich der Maschine prinzipielle Unterschiede bestehen und welchen Einfluß sie auf das Luftspaltfeld haben. Im Mittelpunkt der Untersuchungen stehen niederpolige Luftspaltfelder, der Einfluß der Sättigung auf nutharmonische Felder wird nur schlaglichtartig behandelt. Durch Verwendung bezogener Größen wird eine Übertragbarkeit der numerisch gewonnenen Ergebnisse angestrebt. Diese werden darüber hinaus mit den Ergebnissen eines verbreiteten analytischen Verfahrens verglichen.
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Electrical engineering 81 (1998), S. 151-161 
    ISSN: 1432-0487
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Description / Table of Contents: Contents The spectrum of the magnetic field in the air gap of induction motors is influenced by the level of saturation of the magnetic circuit. This report deals with the effects of saturation, which are significantly different in case of yoke respectively teeth saturation. The research is done by means of numerical field calculations of a simplified model. The results are compared with a commonly used analytical approach. Beside of the reduction of the fundamental field the effects of saturation on the third and fifth space-harmonics are found to be most important. The effect on the slot harmonics is proved to be negligible for the model presented.
    Notes: Übersicht Das Spektrum des Luftspaltfelds ändert sich unter dem Einfluß der Sättigung der Eisenbereiche. Anhand numerischer Feldberechnungen wird gezeigt, daß zwischen der Sättigung im Zahn- und Jochbereich der Maschine prinzipielle Unterschiede bestehen und welchen Einfluß sie auf das Luftspaltfeld haben. Im Mittelpunkt der Untersuchungen stehen niederpolige Luftspaltfelder, der Einfluß der Sättigung auf nutharmonische Felder wird nur schlaglichtartig behandelt. Durch Verwendung bezogener Größen wird eine Übertragbarkeit der numerisch gewonnenen Ergebnisse angestrebt. Diese werden darüber hinaus mit den Ergebnissen eines verbreiteten analytischen Verfahrens verglichen.
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Journal of electronic testing 9 (1996), S. 29-41 
    ISSN: 1573-0727
    Keywords: testing ; mixed-signal ; fault simulation ; arithmetic distance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: Abstract The rapidly evolving role of analog signal processing has spawned off a variety of mixed-signal circuit applications. The integration of the analog and digital circuits has created a lot of concerns in testing these devices. This paper presents an efficient unified fault simulation platform for mixed-signal circuits while accounting for the imprecision in analog signals. While the classical stuck-at fault model is used for the digital part, faults in the analog circuit cover catastrophic as well as parametric defects in the passive and active components. A unified framework is achieved by combining a discretized representation of the analog circuit with the Z-domain representation of the digital part. Due to the imprecise nature of analog signals, an arithmetic distance based fault detection criterion and a statistical measure of digital fault coverage are proposed.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1573-4943
    Keywords: Metalloproteinase ; gelatinase B ; active site
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Gelatinase B (MMP-9), a member of the matrix metalloproteinase family, is a zinc- and calcium-dependent endopeptidase that is known to play a role in tumor cell invasion and in destruction of cartilage in arthritis. It contains a conserved sequence400His-(X)3-His-(X)28-Asp-Asp-(X)2-436Gly, the function of which is under investigation. The conserved Asp-432 and Asp-433 residues were individually replaced with Gly; these substitutions reduced the gelatinolytic activity of the enzyme to 23% and 0%, respectively. Replacing Asp-433 with Glu, however, decreased the gelatinolytic activity of the enzyme by 93% and proteolytic activity of the enzyme for the Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by 79%. The wild-type and D432G and D433E mutant enzymes had similarK m values for the synthetic substrate and similarK i values for the competitive inhibitor, GM6001. Thek cat/K m values for D432G and D433E mutant enzymes, however, were reduced by a factor of ∼4 and their K a Ca values were increased by four- and sixfold, respectively. The significance of His-400 in the activity of the enzyme was assessed by replacing this residue with Ala and Phe. Both H400A and H400F mutants were inactive toward gelatin substrate. These data demonstrate that Asp-432, Asp-433, and His-400 residues are important for the activity of gelatinase B. His-400 may act as a zinc-binding ligand similar to the His-197 in interstitial collagenase (MMP-7) and Asp-432 and Asp-433 residues are probably involved in stabilization of the active site of the enzyme. The His-400 and Asp-433 residues are conserved in all members of the MMP family. Therefore, our results are relevant to this group as a whole.
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  • 10
    ISSN: 1573-5117
    Keywords: Crustacea ; Anostraca ; cysts ; egg bank ; RAPD ; PCR
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Like many diapausing crustaceans, anostracans (Crustacea, Branchiopoda) produce encysted embryos capable of surviving the long periods of desiccation typical of their environments. These cysts are far more abundant and are easier to collect than adults and for some applications they are superior to adults as subjects for genetic analysis. Due to the lack of minimal tissue size requirements, PCR-based analysis is the best alternative for genetic study of cysts. We describe a method for the fast extraction of DNA from cysts, yielding template for RAPD-PCR analysis.
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