ISSN:
1434-4475
Keywords:
Keywords. Allylic substitution; Asymmetric catalysis; Allylic amination.
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary. The chiral diphosphine ligand xylophos (1) was tested as an auxiliary in palladium catalyzed allylic substitution reactions. Whereas its activity was found to be generally good only in the case of 1,3-diphenylprop-2-en-1-yl acetate, a fair level of asymmetric induction was achieved with sodium dimethyl malonate (83%ee) and benzylamine (66%ee) as nucleophiles.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s007060070025
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